Manchester City took a major step towards retaining their Premier League title with a 1-0 win over second-placed Chelsea on Saturday, opening up a 13-point lead at the top of the table for Pep Guardiola's side.
Tottenham Hotspur brutally exposed Liverpool's defensive frailties as Harry Kane plundered two more goals in his side's 4-1 romp at Wembley on Sunday.
Harry Kane's 101st Premier League goal was the difference as Tottenham Hotspur earned a 1-0 win over Arsenal, to continue their fine recent form in north London derbies in front of a Premier League record crowd at Wembley on Saturday.
Jose Mourinho's side have been the most impressive of any of the title contenders.
With United unable to sign a replacement, the pressure will be on 21-year-old England forward Marcus Rashford to deliver the goals in a more central role than he has previously operated in.
Match-by-match facts and statistics ahead of the Premier League fixtures on April 28-30
The club said in a statement that they will observe a period of self-isolation in accordance with league and UK Government protocols on quarantine.
Zlatan Ibrahimovic's 28th goal of the season in all competitions put United ahead and Sunderland's cause became all but impossible after Seb Larsson was sent off close to halftime.
On a seismic day in the history of Chelsea, Romelu Lukaku scored the winning goal in a 3-2 FA Cup fifth-round victory
Liverpool moved into the Champions League qualifying spots after a 3-0 win at Burnley on Wednesday took them above Leicester City and into fourth place with one round of Premier League matches remaining.
In Pep Guardiola's 100th match in charge of the Manchester club, captain De Bruyne led from the front as City outclassed the Gunners, who have now suffered six home games without a win. Images from the EPL matches played on Sunday.
High drama ensued during the English Premier League matches on Wednesday as Spurs manager Jose Mourinho was booked while Brighton stunned Chelsea via Alireza Jahanbakhsh's superb equaliser to deny the Blues victory. Here is all the EPL action in IMAGES from Wednesday's matches.
Mauricio Pochettino's Tottenham Hotspur can cement their status as the top dogs in the capital if they end an eight-year wait and defeat Arsenal in the North London derby on Sunday.
Arsenal's Aubameyang compared to Henry after his derby double
Skipper Robin van Persie scored a hat-trick as Arsenal beat Chelsea 5-3 after twice coming from behind in a remarkable Premier League match of attacking brilliance and defensive mistakes at Stamford Bridge on Saturday.
"When he has the ball at his feet, he can make things happen for himself and he can make things happen for other players. He is a very special player."
Manchester City have completed the signing of midfielder Jack Rodwell from Everton on a five-year contract, the Premier League champions said on Sunday.
News of all that's transpired on and off the football field
IMAGES from the English Premier League matches played on Saturday.
Images from Saturday's action in the Premier League.
Images from the EPL matches played on Saturday
Manchester City tightened their stranglehold at the top of the Premier League on Wednesday by trouncing bottom club West Bromwich Albion 3-0 as nearest rivals Manchester United suffered a chastening 2-0 defeat at Tottenham Hotspur.
Follow the latest developments from all the on-field and off-the-field action in the Premiership.
Officials were forced to call off the opening day of the first Test between England and the West Indies due to bad light and rain which saw only 17.4 overs being bowled.
Trippier suspension temporarily halted by FIFA
City were given a stern test on a wet and windy night at a noisy Kassam Stadium but two goals from Raheem Sterling eventually saw them through.
Everton have been handed the dubious distinction of being the 'dirtiest' Premier League team after a study on the all-time cards and fouls by www.dirtyteams.co.uk.
A round-up off all transpired on and off the football pitch
British media reported that the fee for the 24-year-old would be around 75 million pounds ($96.68 million), making him the club's second most expensive signing after last year's world record deal for French midfielder Paul Pogba.
Premier League champions Chelsea eased past a disappointing Everton with goals from Spaniards Cesc Fabregas and Alvaro Morata sealing a 2-0 victory on Sunday.
A summary of Saturday's matches in the English Premier League.
Images from Premier League matches played on Wednesday.
IMAGES from the EPL matches played on Tuesday
Manchester City produced a blistering first-half performance to win 4-1 at Sunderland in the League Cup third round on Tuesday, inflicting more misery on Dick Advocaat's struggling side.
Substitute Jesse Lingard struck twice in the second half as Manchester United fought back from 2-0 down to earn a 2-2 Premier League draw with Burnley at Old Trafford on Tuesday.
The two previous meetings at Anfield ended in 4-0 and 3-1 defeats for Arsene Wenger's Arsenal teams, but there is a fresh optimism around the club after a successful transfer window.
Ole Gunnar Solskjaer continued his dream start as Manchester United caretaker manager with a 3-1 Premier League win over Huddersfield on his Old Trafford debut in the dugout on Wednesday.
On a day of frenetic spending that took the Premier League total to a record far above one billion pounds ($1.29 billion), Antonio Conte's side also missed out on two of their other targets - Alex Oxlade-Chamberlain and Fernando Llorente.
Former England soccer captain Wayne Rooney received a two-year driving ban on Monday after pleading guilty in a British court to drink-driving
Premier League champions Leicester City beat Everton 3-1 at the King Power Stadium on Saturday as a Jamie Vardy double completed a perfect coronation for Claudio Ranieri's miracle men.